2013年5月2日木曜日

In the Thick of It

A CLINICAL PROBLEM-SOLVING article by Deepak Rao from Brigham and Women's, Boston.
A 52-year-old man presented to the emergency department with an acute onset of palpitations and chest pressure. Two days earlier, epigastric burning, fatigue, weakness, and emesis had developed. On presentation, his heart rate was 200 beats per minute. An electrocardiogram showed an irregular rhythm with high-amplitude, mildly prolonged QRS complexes that were consistent with atrial fibrillation with a rapid ventricular response, left ventricular hypertrophy, and interventricular conduction delay. Intravenous fluids and intravenous metoprolol were given without effect, after which electrical cardioversion was performed and sinus rhythm was restored. He was transferred to a tertiary care hospital for further care.
The patient's medical history was notable for hypertension and renal dysfunction (cause unknown) and renal transplantation.
A transthoracic echocardiogram showed severe, concentric biventricular hypertrophy.
In this case, although the patient's history of hypertension offered a straightforward explanation for the observed hypertrophy, several aspects of his presentation were not consistent with hypertensive cardiomyopathy, including the presence of biventricular hypertrophy and preexcitation which suggested the presence of a metabolic storage disorder.
タイトルは、心筋の肥厚(thickness)と酣(たけなわ)の意のthickを掛けたのでしょうか。

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